Zlatogorov, Semyon Ivanovich

ZLATOGOROV, Semyon Ivanovich (born in 1873), a well-known bacteriologist and epidemiologist. Upon graduating from the Military Medical Academy in 1897, he was retained at the Department of Infectious Diseases and Bacteriology. Zlatogorov's first scientific work, which was awarded a prize by the Military Medical Academy, was conducted during his student years in the laboratory of I. P. Pavlov ("The influence of the removal of the thyroid gland in young animals on the development of their organism, in particular the skull and brain," St. Petersburg, 1897). In 1900, Zlatogorov defended his dissertation on the topic: "On the question of the fate of bacteria in the organism of susceptible and non-susceptible animals" (St. Petersburg, 1900). From 1903, Zlatogorov was a privat-docent at the Military Medical Academy; from 1911, a professor of bacteriology at the Psycho-Neurological Institute in Leningrad (now the State Institute of Medical Knowledge); from 1920, a professor at the Military Medical Academy and the Medical Institute in the Department of Infectious Diseases. In 1924, Zlatogorov moved to Kharkiv as the director of the 1st Ukrainian Sanitary-Bacteriological Institute named after Mechnikov and professor of bacteriology at the Medical Institute. Emerging from the schools of S. S. Botkin and N. Ya. Chistovich, Zlatogorov represents a specialist bacteriologist, epidemiologist, and simultaneously an infectionist. Zlatogorov is known for his works on the variability of bacteria: he was the first to point out the variability of the agglutinability of the cholera vibrio. Furthermore, his works on plague (the biology of the plague microbe and bacillus carriage), on plague-like microbes, on protein and non-specific immunity, and on scarlet fever, in which Zlatogorov, with his students, proves the existence of a filterable virus that activates the streptococcus, are well known. In addition, for measles, Zlatogorov and his collaborators isolated (1926) an anaerobic diplococcus, to which he attributes significance in the etiology of measles. In the field of epidemiology, Zlatogorov is a proponent of the doctrine of endogenous infections. Zlatogorov is a participant and organizer of a number of expeditions within the country and abroad. He proposed a "penta-vaccine" for intestinal infections. Zlatogorov is a founding member of the Leningrad Microbiological Society and its chairman from 1918 to 1922. Zlatogorov has repeatedly been on scientific missions in Western Europe and America and was a delegate to international congresses and conventions. Since 1904, he has been a correspondent for the Tehran (in Persia) Sanitary Council and, since 1927, a corresponding member of the Vienna Microbiological Society. Zlatogorov has published more than 100 works in the field of bacteriology, epidemiology, and infectious diseases (of which more than 30 are in foreign languages). Under his editorship and with his participation, a collective manual on medical microbiology was published: "The Doctrine of Microorganisms" (parts 1-3, Petrograd, 1916-18; Kharkiv, 1928). The most important works of Zlatogorov in recent times: "On the etiology of dysentery" (together with A. Gorodkova and V. Karetnikova, Vrachebnaya Gazeta, 1922, No. 5-6); "Die Variabilität der Mikroorganismen" (Deutsche medizinische Wochenschrift, 1924, No. 24); "On vaccination protecting simultaneously against dysentery and summer intestinal infections" (Vrachebnoye Delo, 1921, No. 20-23); "Experimental scarlet fever" (together with V. Derkach and S. Nasledysheva, Vrachebnoye Delo, 1925, No. 15-17); "Etiology, epidemiology, prophylaxis, and serotherapy of scarlet fever" (Profilakticheskaya Meditsina, 1927, No. 1); "On the etiology and prophylaxis of measles" (together with A. Burova and S. Nasledysheva, Journal of Experimental Biology and Medicine, vol. VII, No. 18, 1927); "On the causative agent of scarlet fever" (together with V. Kudryavtsev and B. Palant, Journal of Microbiology, Pathology and Infectious Diseases, 1928, No. 2).